I am suffering, how to overcome it once for all ?

This is an honest question. A honest question deserves a real honest answer. In Srimad Bhagavatam, the great vedic scripture relished by enlightened spiritualists, there is a description of a great spiritual personality. His name is Bhakta Prahlad. Though he was very young, he had some amazing realizations about life. This is the truth about life, that real wisdom is not in age but in one's mature spiritual understanding. Anyways his deep realization was "To become happy one has to stop acting to be happy".

This might sound confusing but the reality what we identify and live will determine our suffering or happiness. If we identify ourselves with this body, then we have to struggle to keep up with so many things just to project our false identity as a particular body with its characteristics. And anytime there is a  threat to such an identity we feel depressed, morose and try to fight back. So, to transcend suffering one only needs to accept his true existence. Every living entity is spiritual in nature, when he identifies himself with matter and relates everyone with that consicousness he suffers, because his acts are selfish in a way that he is trying to be an independent enjoyer without understanding his real identity as loving co-operator. It is almost like watching a movie, if we are too much absorbed and identify with a character, we feel quite involved feel we are the one who is up there feeling the emotions. This is exactly how the external energy of the Supreme Lord works, it forces us to believe we are these bodies and as we interact in such an environment we suffer or enjoy. It is the nature of the soul to have a loving experience but when one is covered up by material consciousness his enjoyment is based on that false identification.

So, the intelligent question would be, why are we forced to identity with such a material consciousness ? The answer is "because that is exactly what we wanted". We are desiring an existence independent of our origin and dependence. This is impossible in a real sense. But the Supreme Lord is very kind and he wants us to understand that we are not independent by our ability or nature.  He is not like a bad master, but a very loving and kind master and He is willing us to choose our free will so that we can come to a real conclusion that surrendering, depending upon him and relating with him is really our supreme joy.

Lord Krsna in Bhagavad Gita tells us the secret on how to end this suffering. When one realizes that the Supreme Lord is the Supreme Controller, Enjoyer and Friend of everyone one can become very peaceful. People in this world are very insecure because we do not have any shelter.  So, when one accepts one's real identity as a spirit soul and starts practicing the path of purity, he gradually realizes his true nature. When one has this consciousness, even the greatest calamities in this world cannot disturb him, he is always fixed in proper consciousness understanding that  suffering is a temporary phenomenon and he himself is a eternal living spirit. All he has to do is continue to cultivate that eternal consciousness so that he can very soon get liberated forever from this false reality as independent enjoyer. That free will is our doorway towards eternal happiness which puts an end to all kinds of material suffering. Till we come to this conclusion what ever patch work options we choose to become happy will fail ultimately.

And the science which teaches this principle in a step by step process, in a very scientific way is called Bhakt Yoga. So, to actually end ones suffering one has to indeed "stop acting to be happy" by different ways and try to surrender to the Lord with a devotional attitude (Bhakti), which the Lord Himself  taught to the whole humanity in Bhagavad Gita.

Bhakti Yoga is very simple, one has to become a devotee of the Lord instead of become devotee of someone. And the easiest way to purify is to chant the holy names of the Lord - Hare Krsna Hare Krsna Krsna Krsna Hare Hare, Hare Rama Hare Rama Rama Rama Hare Hare.